Local antibacterial and antifungal drugs, actively used in gynecological practice, is the drug Neo-pentotrans.
Active components of the drug - nitratemiconazole and metronidazole - cause its antiprotozoal, antibacterial action. Metronidazole inhibits the reproduction of nucleic acids of microorganisms, which leads to the destruction of their DNA and death. Miconazole disrupts the synthesis of elements of the cell membranes of fungi, which causes their destruction.
The agent has activity towardsanaerobic bacteria, trichomonads, pathogenic fungi, including genus candida, gargantella, anaerobic streptococci. As the review indicates, "Neo-pentotrans" effectively fights some gram-positive bacteria.
A remedy is made in the form of vaginalsuppositories, which contain from 100 to 200 mg of miconazole nitrate, as well as from 500 to 750 mg of metronidazole. The analogue "Neo-Pentotran Forte-L" except for the listed substances contains 100 mg of lidocoin. Preparations that accurately copy the formula "Neo-pentotrana", no. The closest thing is the "Clion-D 100", which contains the same active components, but in other volumes.
Suppositories are prescribed for topical treatment of vaginal mixed infections, bacterial vaginosis. The drug is used for vaginal candidiasis, trichomonas vulvovaginitis.
As the review shows, "Neo-pentotrans" can notapply with severe deviations in the liver, porphyria, ailments of the nervous system, violations of hemopoiesis. Candles are not prescribed for hypersensitivity to active elements, in early pregnancy, children and adolescents under 14 years. In the 2nd and 3rd trimesters the drug is used strictly according to indications. During lactation, if necessary, treatment should stop breastfeeding the baby.
Medication is administered once a day in the eveningtime. The course of treatment is a week. With relapsing vaginitis, the remedy should be used twice - in the morning and in the evening. Therapy is carried out for two weeks. With more prolonged use, as the review indicates, "Neo-pentotrans" can cause signs of an overdose. These symptoms are manifested by epigastric pain, stomatitis, nausea, metallic taste in the mouth, itching. To buy candles "Neo-pentotrans", the price of which is 678 rubles, you can in the pharmacy without a prescription.
The drug can provoke negativereactions of the body that are similar to signs of an overdose. As evidenced by the review, "Neo-pentotrans" can cause itching, burning or irritation of the vaginal mucosa. In addition, dry mouth, abdominal pain, loss of appetite, diarrhea, metallic taste are observed. These symptoms pass after the end of therapy. In rare cases, from the side of the nervous system, there are psychoemotional disorders, headache, ataxia.
