The drug "Gliatilin" is a member of the groupcholinomimetics of the central action with a predominant effect on the central nervous system. The drug contains 40.5% of choline metabolically protected, which provides its release in the brain.
The medication is available in the form of capsules for oral administration and ampoules for intramuscular and intravenous administration.
The active substance is choline alphoscerate. The capsule contains 400 mg of the active ingredient, in the ampoule - 1000 mg.
Active substance, getting into the body,is split into glycerophosphate and choline under the influence of enzymes. Choline participates in the biosynthesis of one of the main mediators in nervous excitation (acetylcholine). Glycerophosphate is a precursor of frasfatidylcholine (phospholipid in the neuronal membrane).
Accumulation occurs mainly in the brain (up to 45% of the blood level), liver and lungs. In the form of carbon dioxide, lungs excrete 85%. 15% goes through the intestines and kidneys.
The drug has no effect on the reproductive cycle, does not have mutagenic and teratogenic properties.
The medicine "Gliatilin" can improve the transmissionin the cholinergic neurons of nerve impulses, cerebral blood flow, positively affect the receptor functions and the plasticity of the neuronal membranes, activate structures in the reticular formation, enhance metabolic processes, restore consciousness in traumatic brain injuries.
The active component of the drug hascorrective and preventive effects on certain pathogenic factors in the involuntary psycho-organic syndrome-a change in the phospholipid composition in the membranes of neurons and a decrease in cholinergic activity.
The drug "Gliatilin" is shown in an acute periodcraniocerebral injuries with predominantly stem-like lesions (coma, impaired consciousness, signs of lesions in the brainstem and others). The drug is prescribed for hemorrhagic and ischemic stroke in the reducing and acute phases. The "Gliatilin" medication is recommended for involuntary or degenerative brain psycho-organic syndromes, the consequences of cerebrovascular insufficiency. These conditions include multi-infarct dementia, Alzheimer's disease, as well as states accompanied by confusion, decreased motivation, ability to concentrate, initiative, development of disorientation. The drug "Gliatilin" instruction recommends when emotional instability, changes in the behavioral sphere, irritability, senile pseudomelanchia, a decrease in interest.
The drug is not prescribed for lactation, hypersensitivity, pregnancy.
The medicine "Gliatilin". Instructions for use
The drug is administered intramuscularly or slowlyintravenously with the development of acute conditions - 1000 mg per day. Inside with cerebrovascular insufficiency of chronic course and syndromes of dementia, the drug "Gliatilin" instruction recommends taking three times a day for 400 mg.
The duration of the course is from three months to six months.
The side effect of the drugis nausea. In case of an overdose, this symptom may increase. If nausea occurs, reduce the dosage of the medication and consult a doctor.
The medicine "Gliatilin" for children is prescribedoften enough. As practice shows the use of the drug in patients aged from one year and older, the medication is transferred quite well. The tool "Gliatilin" for children is a means of promoting the normalization of development. The drug has a positive effect on concentration of attention. Some parents note significant progress in the development of children. Very effective medication with long-term admission (two to three months, a minimum).
